There are some good reasons for a husband to not donate Blood to his wife during her childbearing years. During this time, a women who plans to become pregnant, receiving Blood from her husband may pose a small risk to the infants born of these pregnancies. If, after the Blood transfusion the woman develops an antibody to an antigen on the father’s red Blood cells, and the subsequently born fetus inherits the father’s red cell antigen, the antibody from the mother may enter the Bloodstream of the fetus causing destruction of fetal red Blood cells. This may cause serious anemia in the fetus and excessive jaundice in the infant after birth. This is a known major cause of brain damage. Special Blood transfusions, using selected red Blood cells that do not have the particular in-compatible and offending antigen, are available when this condition is pre-diagnosed. Of course, we suggest autologous Blood donation for the mother. However, for those mothers who are unable to make an autologous donation, the decision to select her husband as a donor should always take this risk under consideration, and specific consultation with your pediatrician on this subject is essential. Blood test results are important in Blood disorders in Blood tests and a Blood test with Rare Blood types.